Apama Medical
Augmenix
Bardy Diagnostics, Inc.
Cardionomic
Cheetah Medical
CHF Solutions
Confluent Surgical
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CSA Medical, Inc.
EBR Systems, Inc.
EKOS Corporation
Hemosphere
Imperative Care, Inc.
Impulse Monitoring
Instylla, Inc.
Interventional Spine
ISTO Technologies
Ivantis, Inc.
MindFrame
Neurolutions
Neuronetics, Inc.
Ocular Therapeutix (NASD:OCUL)
OptiScan BioMedical
PathoGenetix
RefleXion Medical
Rejoni, Inc.
Renovia, Inc.
SeQual Technologies
Sonoma Orthopedic Products
Stereotaxis (NASD:STXS)
SterilMed
STRM.BIO
TomoTherapy (NASD:TOMO)
Truvic
Tulavi Therapeutics
Vascular Pathways
ZONARE Medical Systems
Apama Medical
www.apamamedical.comApama Medical is a privately held medical device company formed by Shifamed LLC, a Silicon Valley based medical device incubator. Apama is focused on the rapidly growing electrophysiology (EP) market in which mapping and ablation is estimated to reach $2.0B in 2017.
Augmenix
www.augmenix.comAugmenix is a medical device company focused on the development and commercialization of radiology oncology products using its proprietary hydrogel technology.
Bardy Diagnostics, Inc.
www.bardydx.comBardy Diagnostics, Inc. ("BardyDx") has developed the Carnation Ambulatory Monitor, a non-invasive P-wave centric ambulatory cardiac monitor and arrhythmia detection device that generates superior clinical data, improves patient compliance and fits within varied hospital and cardiology workflows and reimbursement concerns.
Cardionomic
http://www.cardionomicinc.com/Cardionomic treats reduced cardiac output – ADHF’s root cause – by neuromodulating the terminal branches of the cardiac plexus to benignly increase contractility. Beyond simply relieving dyspnea as current therapies do, Cardionomic’s acute, non-systemic therapy will improve cardiac output, renal blood flow, urine production and pharmacological tolerance
Cheetah Medical
www.cheetah-medical.comCheetah Medical's proprietary NICOM Noninvasive Cardiac Output and Hemodynamic Monitoring System delivers continuous, accurate parameters useful for fluid management and drug titration. The system is FDA-cleared and CE Marked, and since its commercial launch in 2008 has been adopted by a growing number of clinicians worldwide.
CHF Solutions
www.chfsolutions.comCHF Solutions was acquired by Gambro in 2010. The company manufactured innovative medical devices for cardiac care and was the developer of Aquapheresis therapy and the Aquadex FlexFlow Fluid Removal system, a method to remove excess fluid from patients suffering from fluid overload.
Confluent Surgical
www.confluentsurgical.comConfluent Surgical was acquired by Tyco International in 2006. The company pioneered the development and delivery of biomaterials to be used as sealants, for adhesion prevention and homeostasis in many types of surgery.
CSA Medical, Inc.
www.csamedical.comCSA Medical, Inc. develops and manufactures a proprietary interventional spray cryotherapy technology platform comprised of a device and specialty catheters that enable delivery of spray cryogen inside the body to flash freeze and destroy unwanted tissue. The Company is the first to harness the power of low pressure, extremely cold (-196 o C) liquid nitrogen inside the body.
EBR Systems, Inc.
http://www.ebrsystemsinc.com/ EBR Systems develops a wireless cardiac pacing system for heart failure.
EKOS Corporation
www.ekoscorp.comEKOS Corporation is the world leader in providing ultrasound-assisted, fluid infusion catheters for treating blood clots. Other applications which deliver physician-prescribed fluids or contrast agent to other targeted locations in the body are under investigation.
Hemosphere
https://www.merit.com/peripheral-intervention/access/renal-therapies-accessories/merit-hero-graft/Hemosphere was acquired by CryoLife in 2005 and subsequently acquired by Merit Medical Systems. The company was an early stage medical device developer of a vascular access technology for hemodialysis.
Imperative Care, Inc.
Imperative Care is an early-stage privately-held company which is formed to explore technologies and innovations in stroke diagnosis, treatment, and rehabilitation, in order to curtail the disruptive impact of stroke on patients, families, and healthcare systems around the world.
Impulse Monitoring
www.impulsemonitoring.comImpulse Monitoring was acquired by NuVasive, Inc. (NASD: NUVA) in 2011. Impulse Monitoring provides surgical support services to hospitals and other facilities that include intraoperative neuromonitoring (IONM) for spinal, nerve and brain-related surgeries.
Instylla, Inc.
http://www.instylla.com/Instylla is a development-stage company creating a new standard in embolization therapy for use in interventional radiology and oncology that will allow physicians to perform a variety of procedures with shorter procedure times, higher technical confidence and potentially improved efficacy.
Interventional Spine
www.i-spineinc.comInterventional Spine is a medical device company that designs, develops, and markets patented implantable devices for the spine that can be deployed via percutaneous techniques.
ISTO Technologies
www.istotech.comISTO Technologies is an ortho-biologic company focused on developing differentiated products for sports medicine and spinal therapy to repair and regenerate cartilage and bone.
Ivantis, Inc.
www.ivantisinc.comIvantis, Inc. is a company dedicated to the development of new and innovative solutions for glaucoma. Current therapies for primary open angle glaucoma (POAG) include eye drops, laser therapy, and surgery. But each of these has its limitations. Glaucoma remains the leading cause of blindness worldwide, in need of better treatment alternatives. Ivantis’ goal is to develop new and effective solutions for ophthalmology specialists and the 70 million people worldwide who are affected by this debilitating and sight-stealing disease.
MindFrame
MindFrame was acquired by Covidien (NYSE: COV) in 2012. MindFrame was an early-stage company developing a novel mechanical device for the treatment of acute ischemic stroke.
Neurolutions
https://neurolutions.com/Neurolutions is developing brain computer interface technology that uses non-invasive technology to detect brain waves to control movement of prostheses. The company is pursuing the stroke rehabilitation market.
Neuronetics, Inc.
neurostar.com Neuronetics, Inc. is the world’s leader in developing non-invasive therapies for psychiatric and neurological disorders using MRI-strength magnetic field pulses
Ocular Therapeutix (NASD:OCUL)
www.ocutx.comOcular Therapeutix (NASD:OCUL) is developing and commercializing ophthalmic therapeutic products using its proprietary hydrogel technology. The Company is commercializing its ReSureTM Adherent Ocular Bandage for surgical applications and is developing sustained ocular drug delivery products based on its core hydrogel technology. The Company completed an IPO in 2014.
OptiScan BioMedical
www.optiscancorp.comOptiScan BioMedical is the developer of the OptiScanner™, an automated bedside glucose monitoring system intended to assist healthcare providers manage the glucose level of critically ill patients.
PathoGenetix
www.pathogenetix.comPathoGenetix, Inc. (formerly U.S. Genomics) is developing an automated system for identification and strain typing of pathogens in a broad range of complex sample types. Unlike approaches that require specific reagents for detection of each pathogen, PathoGenetix' approach uses a single reagent set to create genomic barcodes which are then used to detect and identify thousands of strains from hundreds of species.
RefleXion Medical
https://reflexion.com/ Reflexion Medical is a commercial-stage medical device company that has developed a therapeutic approach that combines biotargeting with radiation, enabling effective treatment of cancer, including advanced metastatic cancer.
Rejoni, Inc.
Rejoni is a medical device company developing an in-situ forming hydrogel for post-surgical placements in the uterus to prevent the formation of intrauterine adhesions.
Renovia, Inc.
https://renoviainc.comRenovia is a digital health company that is in early commercialization of the leva® Pelvic Digital Health System, an innovative movement-based, interactive and integrated digital health system.
SeQual Technologies
www.sequal.comSeQual was acquired by Chart Industries' (NASD: GTLS) wholly owned subsidiary, Caire inc. in December 2010. SeQual is a leading provider of innovative oxygen concentrators.
Sonoma Orthopedic Products
www.sonomaorthopedics.comSonoma Orthopedic Products specializes in minimally invasive implant systems for addressing problematic fractures in orthopedic trauma care.
Stereotaxis (NASD:STXS)
www.stereotaxis.comStereotaxis (NASD: STXS) completed an initial public offering in 2004. The company is a developer of an innovative catheter navigation platform designed to make the treatment of complex cardiac arrhythmias safe and effective.
SterilMed
www.sterilmed.comSterilMed was acquired by Ethicon Endo-Surgery, a subsidiary of Johnson & Johnson (NYSE: JNJ). The company specializes in medical device reprocessing and small equipment & instrument repair for hospitals and healthcare facilities.
STRM.BIO
https://strm.bio/ Based in Boston, MA, STRM.BIO is a pre-clinical, VC-backed biotechnology company that is leveraging extracellular vesicles (EVs) to deliver gene therapy in a better way: simpler, safer, practical. STRM.BIO’s proprietary non-viral delivery technology addresses current bottlenecks in gene therapy, allowing for targeted delivery of a variety of payloads, with large carrying capacity and the ability to repeat dose.
TomoTherapy (NASD:TOMO)
www.tomotherapy.comTomoTherapy (NASD: TOMO) completed an initial public offering in 2007 and was later acquired by Accuray (NASD: ARAY). The company provides a revolutionary, radiation treatment system that delivers conformal radiation therapy to cancer patients while limiting damage to surrounding healthy tissues.
Truvic
https://www.truvic.com/Truvic is an early-stage medical device company developing devices to remove blood clots in peripheral blood vessels.
Tulavi Therapeutics
www.tulavi.com Tulavi Therapeutics is a development-staqe medical device company dedicated to creating new therapies that directly target the nerves of neurally-mediated peripheral and vicseral disease.
Vascular Pathways
www.vascularpathways.comVascular Pathways, Inc. is a privately-held medical device company focused on commercializing the Accucath Intravenous Catheter System, an FDA approved innovative product enabling rapid, safe, and successful IV insertion.
ZONARE Medical Systems
www.zonare.comZONARE Medical Systems develops, manufactures and sells a high-performance software-based convertible ultrasound solution.